Intracortical convergence of layer 6 neurons
نویسندگان
چکیده
منابع مشابه
Intracortical convergence of layer 6 neurons.
Axonal branches from a subset of neurons in cerebral cortical layer 6 innervate both cortical layer 4 and the thalamus. As such, these neurons are poised to modulate thalamocortical transmission at multiple forebrain sites. Here, we examined the functional organization of the layer 6 intracortical projections in auditory, somatosensory, and visual cortical areas using an optogenetic approach to...
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Layer 6 is the main source of neocortical connections back to specific thalamic nuclei. Corticothalamic (CT) systems play an important role in shaping sensory input, but little is known about the functional circuitry that generates CT activity. We recorded from the two main types of neurons in layer 6, regular-spiking (RS; pyramidal neurons) and fast-spiking (FS; inhibitory interneurons) cells ...
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Layer 6 corticothalamic neurons are thought to modulate incoming sensory information via their intracortical axons targeting the major thalamorecipient layer of the neocortex, layer 4, and via their long-range feedback projections to primary sensory thalamic nuclei. However, anatomical reconstructions of individual layer 6 corticothalamic (L6 CT) neurons include examples with axonal processes r...
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A canonical feedforward circuit is proposed to underlie sensory cortical responses with balanced excitation and inhibition in layer 4 (L4). However, in another input layer, L6, sensory responses and the underlying synaptic circuits remain largely unclear. Here, cell-attached recordings in rat primary auditory cortex revealed that for the majority of L6 excitatory neurons, tonal stimuli did not ...
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The spiking patterns of neocortical pyramidal neurons are shaped by the conductances in their apical dendrites. We have previously shown that the spiking patterns of layer 5 pyramidal neurons change with temperature, probably because temperature modulates the electrical coupling between somatic and dendritic compartments. Here we determine whether temperature has similar effects on the spiking ...
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ژورنال
عنوان ژورنال: NeuroReport
سال: 2012
ISSN: 0959-4965
DOI: 10.1097/wnr.0b013e328356c1aa